Basic Information
VIS ID
TVIS30014257
Fusion event
HIV-NOL11 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
65731432/67735316 (Hg38)
End
65731432/67735316 (Hg38)
Orient
+
Location type
Intronic
Target gene
NOL11
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-766-3p ; hsa-mir-4323 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-340-5p ; hsa-mir-4796-5p ; hsa-mir-3163 ; hsa-mir-1276 ; hsa-mir-3662
Nearest miRNA
hsa-mir-10226/Upstream/263731; hsa-mir-1250/Downstream/689135;
Nearest TSS
ENST00000595228/Upstream/11207; ENST00000577687/Downstream/1264;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17164, chr17-CpG: 104/Downstream/89694
Upstream sequence
aagttttagttacttagtgaatgaatATTCATATACAAATAAATCAAGGCAATAGGATGTTTTGGTAATTTTAATTTGAGGATAAAGAGACAAGGTTTCT
Downstream sequence
CAGCATACAATTTAATTATACTTTATATGTAAAAAAGTAATTTTAACTATTCACAATTTTTTATTGTGAATAAACTCACACTTTTTTATTACAACttatt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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