Basic Information
VIS ID
TVIS30014269
Fusion event
HIV-BRIP1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
59837308/61759947 (Hg38)
End
59837308/61759947 (Hg38)
Orient
+
Location type
Intronic
Target gene
BRIP1
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-378a-5p ; hsa-mir-182-5p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-3689d ; hsa-mir-3929 ; hsa-mir-4254 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-455-3p ; hsa-mir-4649-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-490-3p ; hsa-mir-493-3p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-619-3p ; hsa-mir-6499-3p ; hsa-mir-6500-3p ; hsa-mir-6516-5p ; hsa-mir-6808-5p ; hsa-mir-6851-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7854-3p ; hsa-mir-940
Nearest miRNA
hsa-mir-10226/Upstream/1716842; hsa-mir-1250/Downstream/1184268;
Nearest TSS
ENST00000595228/Upstream/168745; ENST00000635817/Downstream/16533;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/297474, chr17-CpG: 21/Downstream/103517
Upstream sequence
gacttgcttgacacagggttgccacaaacctttaatttatgaaaaaaaaaaaacccagaatatttgcaaagtgcgataaagcaaagcacaataaaataag
Downstream sequence
gtattcctgtacagaatatcccattcaagagcaacagaatacacattcttctcaaataccataaaatagtctccaggatagattatatattaggccatga
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate