Basic Information
VIS ID
TVIS30014272
Fusion event
HIV-RPTOR integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
78590043/80616243 (Hg38)
End
78590043/80616243 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPTOR
miRNAs that regulate target gene
hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-10226/Upstream/196750; hsa-mir-1250/Downstream/509033;
Nearest TSS
ENST00000595228/Upstream/70577; ENST00000572733/Downstream/92690;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/70960, chr17-CpG: 30/Downstream/110784
Upstream sequence
TGGAAGGAAAATTAGCCCTGAATGAATGACTCAGTCCCATGATAATGTGGCTAATTTTAATTTGCATCAGGAATAGTAAAGCTGTGGCCCAGTGTGTTAT
Downstream sequence
CAAATAAATCTCTAAACAGCCTTGAAATCAATCCATTTATTGAAAATTGAAAATCtttttttttttttttttttttgagacggagtctcactctgttgcc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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