Basic Information
VIS ID
TVIS30014276
Fusion event
HIV-SHISA5 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
48536900/48499466 (Hg38)
End
48536900/48499466 (Hg38)
Orient
-
Location type
Intronic
Target gene
SHISA5
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-1296-5p ; hsa-mir-877-5p ; hsa-mir-92a-3p ; hsa-mir-885-3p
Nearest miRNA
hsa-mir-12127/Upstream/183007; hsa-let-7g/Downstream/50495;
Nearest TSS
ENST00000440867/Upstream/19907; ENST00000421275/Downstream/4584;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/52289, chr3-CpG: 22/Downstream/4399
Upstream sequence
AAATGCTCCTGCTTTTAAAAAAAGAAATACCATcaggcgcggtggctcatgcctgttatcccagcactttggcaggccaagatgggcagatcacctgagg
Downstream sequence
tcaggagttcaagaccagcttggtgaacatggtgaaaccccatctctagtaaaaatacaaaaattaggccgggcgtggtggcgggcgcctgtagttccag
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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