Basic Information
VIS ID
TVIS30014278
Fusion event
HIV-VAV1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
6838138/6838127 (Hg38)
End
6838138/6838127 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
VAV1
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1227/Upstream/101349; hsa-let-7e/Downstream/779312;
Nearest TSS
ENST00000633603/Upstream/2318; ENST00000596944/Downstream/49439;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/69978, chr19-CpG: 25/Downstream/236614
Nearest cancer related gene
VAV1(OG, No orient, 0)
Upstream sequence
caaatttattagctggtgttctgctgcaagaaagagctgtcctttctgccctcatctgtctgtctgtctgtctatctatctatctatctatctatctatc
Downstream sequence
tatctatccatgcatccatcttttatctatatatcatctatctatttacctatcatctatttgcctatcacctatctacccatctattatctatctatat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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