Basic Information
VIS ID
TVIS30014281
Fusion event
HIV-CCDC106 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
56161823/55650457 (Hg38)
End
56161823/55650457 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
CCDC106
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-let-7e-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-4736 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-181d-3p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-4655-5p
Nearest miRNA
hsa-let-7e/Upstream/262215; hsa-mir-10394/Downstream/2684231;
Nearest TSS
ENST00000633603/Upstream/1538; ENST00000592867/Downstream/3689;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1886, chr19-CpG: 290/Downstream/1839
Upstream sequence
TAATACATTTTGGACCCCAGCCCCATCCTCTTCCCCGGATGGTCAGGCCGTTTGCCCGACAGCCCATGGCCTGGAGAACCCACACTCTACCCCACCTACC
Downstream sequence
CTCATCTCAGCCTTGCTAGCTCCTTGGCTGGGAAGACCCCTCAAAAGCTCCCACATCTCTCTTTGTGAATTCAACCCTTTCCCCAAAAATCCTAGGCAAG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate