Basic Information
VIS ID
TVIS30014283
Fusion event
HIV-RPSAP58 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
23968167/23785365 (Hg38)
End
23968167/23785365 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
RPSAP58
miRNAs that regulate target gene
hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-3163 ; hsa-mir-411-5p ; hsa-mir-3121-3p ; hsa-mir-574-5p ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-342-3p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-4738-3p
Nearest miRNA
hsa-mir-10395/Upstream/3386011; hsa-let-7e/Downstream/11337335;
Nearest TSS
ENST00000633603/Upstream/26474; ENST00000531821/Downstream/89336;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/22039, chr19-CpG: 32/Downstream/186290
Upstream sequence
tgcactcaggttatgtgaatttgctttttttccctaagccctgaatattttgcaagttaggacatattactagccccaacacctataaaaagggaggctt
Downstream sequence
ctgcttgggccctttctacagggccttgtgacatatctctgcatcagtcacctaggagatgtgactctccatttttgcctacactctgcccacagaaaaa
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate