Basic Information
VIS ID
TVIS30014285
Fusion event
HIV-PPP5D1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47090015/46586758 (Hg38)
End
47090015/46586758 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PPP5D1
miRNAs that regulate target gene
hsa-mir-2355-5p ; hsa-mir-1972 ; hsa-mir-4761-5p ; hsa-mir-6749-3p ; hsa-mir-6715b-3p ; hsa-mir-4772-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5000-5p ; hsa-mir-7641 ; hsa-mir-4695-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6890-3p
Nearest miRNA
hsa-mir-10395/Upstream/567709; hsa-let-7e/Downstream/122524;
Nearest TSS
ENST00000633603/Upstream/90260; ENST00000602169/Downstream/14167;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/72897, chr19-CpG: 122/Downstream/13771
Upstream sequence
acctaaacatagaaaaggtatagtaaaaatacagtattataatcttatagaccaccatcatgtatgtggtccatcactgaccaaaatgtcattatatggt
Downstream sequence
gcacgactgtatatctttgtaaccttagatatgacatcatggcttcttagatattacatcacaagtacatgcaataaaaaaatacatacaaattagacct
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate