Basic Information
VIS ID
TVIS30014287
Fusion event
HIV-NADK integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
1705810/1774371 (Hg38)
End
1705810/1774371 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
NADK
miRNAs that regulate target gene
hsa-mir-425-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-12136/Upstream/434663; hsa-mir-101-1/Downstream/1353604;
Nearest TSS
ENST00000473358/Upstream/15796; ENST00000412228/Downstream/4048;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/13747, chr1-CpG: 151/Downstream/3584
Upstream sequence
ccaggctggagtgcagtggcgcgatctcggctcaccgcaaactctgcctcccaggttcaagcaattctcctgcctcagcttcccaagtagctgggactac
Downstream sequence
aggtgtgcgccaccacgcccagctaattttgtatttttagtggagacctgcctcttaattctccaacatggaggggtttctccatgttggtcaggctggt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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