Basic Information
VIS ID
TVIS30014291
Fusion event
HIV-STAT5B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
40395643/42243625 (Hg38)
End
40395643/42243625 (Hg38)
Orient
-
Location type
Intronic
Target gene
STAT5B
miRNAs that regulate target gene
hsa-mir-23b-3p ; hsa-mir-1229-3p ; hsa-mir-93-3p ; hsa-mir-324-3p ; hsa-mir-134-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-335-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-526b-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-4762-5p ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-106b-3p ; hsa-mir-150-5p ; hsa-mir-28-5p ; hsa-mir-182-3p ; hsa-mir-28-3p
Nearest miRNA
hsa-mir-1180/Upstream/726408; hsa-mir-10226/Downstream/251148;
Nearest TSS
ENST00000595228/Upstream/25754; ENST00000592536/Downstream/24962;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/59034, chr17-CpG: 126/Downstream/32308
Upstream sequence
gtcgtctgcatcttactttggcaggagaaacggaagagtgacagtggtggggagtgtgggaaagtaaatctaacaactgtgaacactggctcaacctagg
Downstream sequence
tgaagtatatgcgagtactcattgttctattctttccacttttaagtcatgtacacttttttcaaaatcaaaaTGAAGGGCAAACATTCCAAAAAAGAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate