Basic Information
VIS ID
TVIS30014294
Fusion event
HIV-NSUN2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p15.31
Reference genome
GRCh37/hg19
Start
6628123/6628010 (Hg38)
End
6628123/6628010 (Hg38)
Orient
-
Location type
Intronic
Target gene
NSUN2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-193b-3p ; hsa-mir-149-5p ; hsa-mir-125b-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-4277/Upstream/4919142; hsa-mir-10397/Downstream/199843;
Nearest TSS
ENST00000502646/Upstream/2372; ENST00000504286/Downstream/5032;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/44316, chr5-CpG: 149/Downstream/4617
Upstream sequence
TAAGAAAAAATCCTATTTGGGCTTTTTAGAGGATAAGTTAAAAGGACCACTGTCATCTTTGCATATTAAAAATTCTCAAGTGGTAAGGACTCTGTAAATA
Downstream sequence
TATACAACATCTATGACAAACCATCCTCAATCTAGACATTAAAAAGCACGTAACAggcgaggtgcagtggctcatgcctgtaacaccagcactttgggag
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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