Basic Information
VIS ID
TVIS30014295
Fusion event
HIV-PRPF6 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62638067/64006714 (Hg38)
End
62638067/64006714 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRPF6
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-149-5p ; hsa-mir-23b-3p ; hsa-mir-7977 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4746-3p ; hsa-mir-4798-3p ; hsa-mir-6750-3p ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-1/Upstream/63988; hsa-mir-6813/Downstream/70241;
Nearest TSS
ENST00000382410/Upstream/25579; ENST00000444463/Downstream/27630;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/25280, chr20-CpG: 28/Downstream/22894
Upstream sequence
cggccTTTGGACCAGCTCTCTTGACAGGAGGGTCCAAGGAGGCGGAGACGGGACTCTTGGCAGTGGAGACGGGACTTGTGGCAGCGGAGATGGGACTTGA
Downstream sequence
GCCATTCAGACATCACTGTTTATTCCTAGACCCGTGTGTTCTGGCTGTGAGATCCAGCCGGGATTGGTGTCTATTCACAGCATTTGTGGCATCCTACTGG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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