Basic Information
VIS ID
TVIS30014300
Fusion event
HIV-DOCK10 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
225768976/224904259 (Hg38)
End
225768976/224904259 (Hg38)
Orient
+
Location type
Intronic
Target gene
DOCK10
miRNAs that regulate target gene
hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-26b-5p ; hsa-mir-21-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10b/Upstream/4997694; hsa-mir-1244-1/Downstream/106202;
Nearest TSS
ENST00000437798/Upstream/18005; ENST00000636099/Downstream/42646;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/318488, chr2-CpG: 114/Downstream/137677
Upstream sequence
TATCTTAATTTTTCCATTACATTTTTAAAGTCATTAAATAAACATGGCTTTAAATTTATTTTGTAAAAAGTACACACCCAATAAAAAGTTCCTTAACTTC
Downstream sequence
CAACAAGATTTTCATCAGCAAGACCTTCATTAGTGAATGAAGAGCCTTATTTTTCAAAAAATAAAAATCCAAAACCCCCAAAACAAAACCAAAATAAAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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