Basic Information
VIS ID
TVIS30014303
Fusion event
HIV-RBL1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
35710474/37082071 (Hg38)
End
35710474/37082071 (Hg38)
Orient
+
Location type
Intronic
Target gene
RBL1
miRNAs that regulate target gene
hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-580-3p ; hsa-mir-526b-5p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-6806-5p ; hsa-mir-5685 ; hsa-mir-4690-3p ; hsa-mir-4717-5p ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-6815-3p ; hsa-mir-6882-3p ; hsa-mir-22-3p ; hsa-mir-646 ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-5089-5p ; hsa-mir-6878-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-6778-3p ; hsa-mir-4707-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-212-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-186-3p ; hsa-mir-6838-3p ; hsa-mir-6507-3p ; hsa-mir-150-5p ; hsa-mir-5698 ; hsa-mir-8057 ; hsa-mir-143-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6722-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-6813-3p
Nearest miRNA
hsa-mir-103a-2/Upstream/1627974; hsa-mir-1-1/Downstream/1434492;
Nearest TSS
ENST00000382410/Upstream/14016; ENST00000598590/Downstream/13714;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/130023, chr20-CpG: 57/Downstream/13476
Nearest cancer related gene
RBL1(TSG, No orient, 0)
Upstream sequence
GTCACTTCATGGTTGCCAAAATGTCAACTGGCCAGGAGACATAGGGCAGCAGCAGCCCCTAGAAGACAGCACAGAGCATGTGTCTCTATGCCGGGGGAGC
Downstream sequence
CTGCAAGGCTGGGCCAGGATCATAAGGTTTCTCCCTCACTAAGGGACAACGCAGGGGCCTAGGGACAAGAATACAACCAGAAACCCCAGGGACCTGCGTA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate