Basic Information
VIS ID
TVIS30014307
Fusion event
HIV-chr8 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
126986564/125974320 (Hg38)
End
126986564/125974320 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/1152262; hsa-mir-10400/Downstream/1821642;
Nearest TSS
ENST00000518652/Upstream/23071; ENST00000500180/Downstream/26681;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/542122, chr8-CpG: 180/Downstream/582111
Nearby gene
LINC00861(No orient, 23123)
Upstream sequence
TCACTGTCCTGCCTGGCCAACATAATGAATGATAACATTCTGACCAGAGATTCAAATTCCTAAGACCTTCCCTGGTTTTGGTTGAAAATTAGGGCAGTTG
Downstream sequence
TTACCAAGGTCATCGAGGCCATACTTTTTTTTCCAGTGTATGTAGCGGTTCCCAAATGGGTCAAAATTGATTACATGCCTGAGAGTTTTTGAGGTGAAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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