Basic Information
VIS ID
TVIS30014313
Fusion event
HIV-RPS11 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50001496/49498239 (Hg38)
End
50001496/49498239 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
RPS11
miRNAs that regulate target gene
hsa-mir-4433b-5p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-6763-3p ; hsa-mir-3194-3p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-5582-5p
Nearest miRNA
hsa-mir-10395/Upstream/189371; hsa-let-7e/Downstream/2546;
Nearest TSS
ENST00000633603/Upstream/1773; ENST00000598491/Downstream/8577;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/1657, chr19-CpG: 28/Downstream/15035
Upstream sequence
AGACTGAGGTGGCATCTCTGGGAAGCCCCAGAATCTCAGGATTTGTATATCATATGTTCTTCAGAATCAAAGCGTTCTAcagggtgaatatctctacctg
Downstream sequence
aaatgcttggaaccagattttggaatgttctcgcatacatagtgagatgttttggggatgtgacataggtctaaacaagaagctcatttgtttcatatac
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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