Basic Information
VIS ID
TVIS30014316
Fusion event
HIV-chr18 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
52563777/54896546 (Hg38)
End
52563777/54896546 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1659356; hsa-mir-122/Downstream/582675;
Nearest TSS
ENST00000575820/Upstream/12189; ENST00000587660/Downstream/1537;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/67770, chr18-CpG: 39/Downstream/62740
Nearby gene
RAB27B(No orient, 1030)
Upstream sequence
TTGCATTACAGCTTAGGAAGCCTATACACTAATTAAGATTTAACTAAAGCTATGTTATAGGTACTCAATGTTTTGTGATGGTAATCTGACTTTTGCAATT
Downstream sequence
ACCATAGTTTTGGACCATTTCGCTGAGAAAGACAAAAGACTGTCCATTACCAAAAGGATAAAAATTAAAACCAGCAAGATTACAAGAGAGGATTTCATCT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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