Basic Information
VIS ID
TVIS30014321
Fusion event
HIV-RAP1B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
69025215/68631435 (Hg38)
End
69025215/68631435 (Hg38)
Orient
-
Location type
Intronic
Target gene
RAP1B
miRNAs that regulate target gene
hsa-mir-518b ; hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-28-5p ; hsa-mir-139-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-875-3p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-3978 ; hsa-mir-8062 ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-101-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-651-3p ; hsa-mir-3613-3p ; hsa-mir-4495 ; hsa-mir-494-3p ; hsa-mir-4261 ; hsa-mir-4496 ; hsa-mir-100-5p ; hsa-mir-580-3p ; hsa-mir-513a-5p ; hsa-mir-27b-3p ; hsa-mir-3681-3p ; hsa-mir-27a-3p ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-6883-3p ; hsa-mir-642b-5p ; hsa-mir-454-5p ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-510-3p ; hsa-mir-422a ; hsa-mir-378i ; hsa-mir-378h ; hsa-mir-378f ; hsa-mir-378e ; hsa-mir-378d ; hsa-mir-378c ; hsa-mir-378b ; hsa-mir-378a-3p ; hsa-mir-4638-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-518f-3p
Nearest miRNA
hsa-let-7i/Upstream/2380278; hsa-mir-1178/Downstream/641722;
Nearest TSS
ENST00000382841/Upstream/20410; ENST00000541968/Downstream/18809;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/19838, chr12-CpG: 38/Downstream/55365
Upstream sequence
CACATATTACTCATATTTTAATGAAATGCTTACCATGCCTAGATGTATTGTTCAGCCTTCTACTGTTAGAACTTCTTTCGTTAATTTAAAAGTATCTTTA
Downstream sequence
GTTTTCTCAGTATTCATGTTTATCTTCAAAATGTCTATTGTTGTTGCTTATTAAATGAGTCAGAGCTCTTCACTGATACTCAGAGATCTCCTTAATCTTA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate