Basic Information
VIS ID
TVIS30014324
Fusion event
HIV-CDC14A integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
100860318/100394762 (Hg38)
End
100860318/100394762 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1E
Target gene
CDC14A
miRNAs that regulate target gene
hsa-mir-503-5p ; hsa-mir-424-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-628-3p ; hsa-mir-630 ; hsa-mir-301a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/113454; hsa-mir-11399/Downstream/7502461;
Nearest TSS
ENST00000473358/Upstream/31601; ENST00000469387/Downstream/28970;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/41419, chr1-CpG: 146/Downstream/144250
Upstream sequence
AGTTACAGTCTTGAGAAGCAGTGTGAAGTGATTATTCTTGAACTGGTCATGTCCCAATTGATTTTTCTAATTTTGTAACTGTATTCCCCAGAGGGCTTTT
Downstream sequence
TGACACAAACCCTTAATACACACGGAACTAAAAATTGGCAGTGGATCCTTAAAGAGAATTTTATGCCTTTCTTCGTATTGTTTGTATGTATTTACTTGTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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