Basic Information
VIS ID
TVIS30014327
Fusion event
HIV-DGCR2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19080327/19092814 (Hg38)
End
19080327/19092814 (Hg38)
Orient
+
Location type
Intronic
Target gene
DGCR2
miRNAs that regulate target gene
hsa-mir-346 ; hsa-mir-484 ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-3198-1/Upstream/1111853; hsa-let-7a-3/Downstream/870939;
Nearest TSS
ENST00000624155/Upstream/26910; ENST00000456035/Downstream/28715;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/62408, chr22-CpG: 115/Downstream/28741
Upstream sequence
aaaaaataagaaatacttaggtataaatctaacaaaagatgtgaagtcctgtacactgaaaaattttcaacattgctgagaaaaaACattttttaaagac
Downstream sequence
ctaggtgcaaaggcagctccctgaagaaagaacaggcctttcaacagaatggtactgCGAAACACggaagaaagaaaaatgaagaggaggaggaggagga
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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