Basic Information
VIS ID
TVIS30014334
Fusion event
HIV-APEH integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
49720636/49683203 (Hg38)
End
49720636/49683203 (Hg38)
Orient
+
Location type
Intronic
Target gene
APEH
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-30a-5p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-186-5p
Nearest miRNA
hsa-mir-12127/Upstream/409017; hsa-let-7g/Downstream/122934;
Nearest TSS
ENST00000440867/Upstream/602; ENST00000629802/Downstream/1887;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/8357, chr3-CpG: 122/Downstream/2507
Upstream sequence
TGGAGTATTACCGTGCCCTCAAGACCCGGAATGTGCCTGTTCGGTGAGTGCAGCATGAAGGCCCTGGCAGCTGGTGGGCAGGTGAGCACAGGAGGACCCT
Downstream sequence
CCAACCTTAAATGTTGCTGACTAATCCCTACAGGCTCCTGCTCTATCCCAAAAGCACCCACGCATTATCAGAGGTGGAGGTGGAGTCAGACAGCTTCATG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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