Basic Information
VIS ID
TVIS30014337
Fusion event
HIV-CPNE1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
34250190/35662268 (Hg38)
End
34250190/35662268 (Hg38)
Orient
-
Location type
Intronic
Target gene
CPNE1
miRNAs that regulate target gene
hsa-let-7d-5p ; hsa-mir-1229-3p ; hsa-mir-500a-5p ; hsa-mir-532-5p ; hsa-mir-378a-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/208171; hsa-mir-1-1/Downstream/2854295;
Nearest TSS
ENST00000382410/Upstream/8591; ENST00000397416/Downstream/2290;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/42509, chr20-CpG: 46/Downstream/2366
Upstream sequence
AAGGCAGCAAATCAGAAGACATTTCTAAATAAGATATTCCTCCTGTCAAAAATATTAAGTTATGTTTCAATCCCCCCAAATGCCAACAAAAATGTTGCTA
Downstream sequence
CCTTCATTTTCACTTCAGAGCAAAATTATACTTCTAACCTAAACAACCACATTCACTCTGTTTTTGAGTCTTAAAAGCTGGCTTTAAACTTAATTAAATT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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