Basic Information
VIS ID
TVIS30014347
Fusion event
HIV-CARD11 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
2993625/2953991 (Hg38)
End
2993625/2953991 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
CARD11
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-330-5p ; hsa-mir-146b-5p ; hsa-mir-218-5p ; hsa-mir-539-5p
Nearest miRNA
hsa-mir-339/Upstream/426846; hsa-mir-10399/Downstream/1834574;
Nearest TSS
ENST00000635602/Upstream/9956; ENST00000478527/Downstream/89854;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/25029, chr7-CpG: 35/Downstream/89516
Nearest cancer related gene
CARD11(OG, No orient, 0)
Upstream sequence
gtgatttgcagcccaaagcctcctaactaataAAGACATCTACTTAGTACAAAGACTTGCTCAGCACCATGAATGCACAAGAGAGCTGAAAGGCAGGTGT
Downstream sequence
TAAGAAGCTTATACCTTTTGCGGGGTCAGAAGGCACAGGCCTAGGAATTAAACAGCAGCTCAAGGCAAGAAGACAGGCAGGTCTGGATAGACCAACCAGC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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