Basic Information
VIS ID
TVIS30014352
Fusion event
HIV-SNX4 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
125222378/125503534 (Hg38)
End
125222378/125503534 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNX4
miRNAs that regulate target gene
hsa-mir-125a-5p ; hsa-mir-10a-5p ; hsa-mir-100-5p ; hsa-mir-218-5p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-3144-3p ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-203a-3p ; hsa-mir-345-3p ; hsa-mir-511-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-10b-5p ; hsa-mir-504-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-3658 ; hsa-mir-580-3p ; hsa-mir-3653-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-7162-3p ; hsa-mir-32-3p ; hsa-mir-944 ; hsa-mir-6507-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p
Nearest miRNA
hsa-let-7g/Upstream/351982; hsa-mir-12124/Downstream/286870;
Nearest TSS
ENST00000440867/Upstream/42733; ENST00000610060/Downstream/1210;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/128013, chr3-CpG: 59/Downstream/16118
Upstream sequence
TTCTGGTGAGTTTTTATTTCCTACTCCATAATTTGTCTTTTCTATTTTTACTCACCAAGTTCTTTTTCTTTGTTTTTTAAAGGTGTCTACTTCCCTTTAT
Downstream sequence
TCTTAATTTACTCCAAGTTCTAAAGCACCAATCTCAATGTTTCTGTTTGTTAATTTTTTGTAACTCCCAACTGTCCTAAGAGGATTCAGACCTTATTCTC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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