Basic Information
VIS ID
TVIS30014353
Fusion event
HIV-ARHGEF3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
56800202/56766174 (Hg38)
End
56800202/56766174 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF3
miRNAs that regulate target gene
hsa-mir-138-5p ; hsa-mir-373-3p ; hsa-mir-335-5p ; hsa-mir-769-5p ; hsa-mir-377-5p ; hsa-mir-485-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-889-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p
Nearest miRNA
hsa-let-7g/Upstream/913580; hsa-mir-12124/Downstream/3851631;
Nearest TSS
ENST00000440867/Upstream/82937; ENST00000495939/Downstream/9393;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/82544, chr3-CpG: 57/Downstream/35448
Upstream sequence
CAGTGGTTTTGAACTTTCCCCCAATTTTCTTCCTCTACTTGCTAATATACCTTAGACAACTTTTATCAAGTAGAACTTTTACAATCTCTAGAGCAGGACT
Downstream sequence
ACCTACCTTTCTGTATTGACTCTCTCCCCATTAAGTCTAGGCAGAATAAATAACACAGTAGATCCAAATAACATTAATGGAGACCACTAATTTATCATAT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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