Basic Information
VIS ID
TVIS30014356
Fusion event
HIV-SPG11 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
44942040/44649842 (Hg38)
End
44942040/44649842 (Hg38)
Orient
-
Location type
Intronic
Target gene
SPG11
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-22-3p
Nearest miRNA
hsa-mir-1233-1/Upstream/856083; hsa-mir-10393/Downstream/68002;
Nearest TSS
ENST00000557528/Upstream/27976; ENST00000632133/Downstream/1802;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/112091, chr15-CpG: 63/Downstream/13251
Upstream sequence
aatttagccaggtgtggtggcgggcacctgtaatcccagctactcgggagggtgaggcaggagaatcacttgaacctgggaggcggaggttgcagtgagc
Downstream sequence
cagatcacaccattgcactccagccagggagacaagagtgagactccatatcaaaaaaaaaaaaaaGCACTAAACCCCACATTTCTACTTTATATTATCT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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