Basic Information
VIS ID
TVIS30014359
Fusion event
HIV-TCFL5 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
61486452/62855100 (Hg38)
End
61486452/62855100 (Hg38)
Orient
-
Location type
Intronic
Target gene
TCFL5
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-193b-3p ; hsa-mir-331-3p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-1-1/Upstream/290087; hsa-mir-124-3/Downstream/323400;
Nearest TSS
ENST00000382410/Upstream/18178; ENST00000497101/Downstream/6663;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/14196, chr20-CpG: 130/Downstream/5667
Upstream sequence
TcaacgtacggtgtaaggctttccacatagcaggtactcaataaatgtctattaaataaatgTCGGAGCAAAATGCCCTTCATAATTCACAGTAGGGTGA
Downstream sequence
GGAAGGCCCTCAGTTAGTCCATGTGTATAAAAGTATCATAAAAAGATATTAGCTAGCtttttaattttctttctttgggggatgggtctcactttgtggc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate