Basic Information
VIS ID
TVIS30014363
Fusion event
HIV-TAF12 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
28964156/28637644 (Hg38)
End
28964156/28637644 (Hg38)
Orient
-
Location type
Intronic
Target gene
TAF12
miRNAs that regulate target gene
hsa-mir-92b-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-6878-5p ; hsa-mir-4271 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4668-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-3202 ; hsa-mir-7515 ; hsa-mir-6124 ; hsa-mir-6783-5p ; hsa-mir-6760-5p ; hsa-mir-5584-5p ; hsa-mir-548k ; hsa-mir-8054 ; hsa-mir-548av-5p
Nearest miRNA
hsa-mir-12136/Upstream/2083051; hsa-mir-101-1/Downstream/2101512;
Nearest TSS
ENST00000473358/Upstream/19614; ENST00000420776/Downstream/5361;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/44702, chr1-CpG: 38/Downstream/5397
Upstream sequence
gtcccagctactcgggaggctgaggtaggagaagtgcttgaacccgtgaggcggaggttgcagtgagccgagatcacaccactgcactccagcctgggcg
Downstream sequence
acagagcaagactccgtctccagaaaaaaGATTTTCTTTTTTTTATTTTTGCTCTCTTTACCCTCCCTGTCTGACTTAAATTAAGTCCATACACAGAAAT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate