Basic Information
VIS ID
TVIS30014369
Fusion event
HIV-APPBP2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
58594086/60516725 (Hg38)
End
58594086/60516725 (Hg38)
Orient
-
Location type
Intronic
Target gene
APPBP2
miRNAs that regulate target gene
hsa-mir-148a-3p ; hsa-mir-4452 ; hsa-mir-670-5p ; hsa-mir-513a-5p ; hsa-mir-2052 ; hsa-mir-6128 ; hsa-mir-6791-5p ; hsa-mir-4308 ; hsa-mir-4292 ; hsa-mir-3681-3p ; hsa-mir-3938 ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-128-3p ; hsa-mir-144-3p ; hsa-mir-4497
Nearest miRNA
hsa-mir-10226/Upstream/473620; hsa-mir-1250/Downstream/2427490;
Nearest TSS
ENST00000595228/Upstream/51564; ENST00000559739/Downstream/9213;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/94754, chr17-CpG: 64/Downstream/8936
Upstream sequence
tgggtatttggacagtttccacctttgggctattatgaatagcagtgctatgaacattcataagtgtatatatcttgaagtagcattactgggttacagg
Downstream sequence
gtatgtttatgttcagttttagtagataatgctgcttttccaaaatggcatatcaacttatattcccattaacaatgtatgagagttttttatttctcca
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate