Basic Information
VIS ID
TVIS30014374
Fusion event
HIV-TMEM177 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
120475209/119717633 (Hg38)
End
120475209/119717633 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
TMEM177
Nearest miRNA
hsa-mir-1285-2/Upstream/5996265; hsa-mir-10b/Downstream/7705904;
Nearest TSS
ENST00000437798/Upstream/38430; ENST00000460162/Downstream/41998;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/38199, chr2-CpG: 86/Downstream/41857
Nearby gene
TMEM177(No orient, 35515)
Upstream sequence
TGATTACTAGGCCACAGCTTCTTGGAACCTCTCTCAGTTCCCCCATGGCTGACTTTGCCATTGACTTGAGTCtttttttttttttttttttttgagacag
Downstream sequence
agtcttgctctgtcacccaggctggagtgcagtggcgcaatcttggctcactgcaacctccacctcccgggttcaagcaattctcctgcctcagcctccc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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