Basic Information
VIS ID
TVIS30014386
Fusion event
HIV-RASAL3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
15571703/15460892 (Hg38)
End
15571703/15460892 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
RASAL3
miRNAs that regulate target gene
hsa-mir-615-3p
Nearest miRNA
hsa-mir-10395/Upstream/11284; hsa-let-7e/Downstream/2821185;
Nearest TSS
ENST00000633603/Upstream/2775; ENST00000601005/Downstream/3622;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/2476, chr19-CpG: 60/Downstream/8679
Upstream sequence
caagcagtgctctctgctcagcctcccgagtagcttggactatagctgcgcactgccctgcctggctcctgcactctctattggcttcccataaacaacc
Downstream sequence
cctagagaaaggttatttcattagcttcatttgacagactgggactctgaggcccaaagagggtcagcaacctgctccagatcacccagcaagagtgCCC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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