Basic Information
VIS ID
TVIS30014392
Fusion event
HIV-CROT integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.12
Reference genome
GRCh37/hg19
Start
87002548/87373232 (Hg38)
End
87002548/87373232 (Hg38)
Orient
+
Location type
Intronic
Target gene
CROT
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-106b-5p ; hsa-mir-221-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p
Nearest miRNA
hsa-mir-10525/Upstream/11457963; hsa-mir-10399/Downstream/4830783;
Nearest TSS
ENST00000635602/Upstream/11789; ENST00000469785/Downstream/2003;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/27460, chr7-CpG: 69/Downstream/102175
Nearest cancer related gene
CROT(OG, No orient, 0)
Upstream sequence
ttgtagcgatgctagtaagggtaaagtgggatctcgttgtagtttatatttgataatgatgttaaagattttttcacatgcattttggccatttgtatat
Downstream sequence
atcttccttggagagatgtctaatcagatacttggccaatttttaaattagtttgtttttttattattgaattgtaatcgttctttagatataagtcttt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate