Basic Information
VIS ID
TVIS30014394
Fusion event
HIV-NOD2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
50753403/50719492 (Hg38)
End
50753403/50719492 (Hg38)
Orient
+
Location type
Intronic
Target gene
NOD2
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-122-5p ; hsa-mir-10a-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c
Nearest miRNA
hsa-mir-1225/Upstream/426817; hsa-mir-11401/Downstream/22813;
Nearest TSS
ENST00000527434/Upstream/7298; ENST00000564634/Downstream/21224;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/45362, chr16-CpG: 110/Downstream/22222
Upstream sequence
CTTCCTTGCTGGGATCTTCCCCCACCCCTAGCCTTGGCCCTCCCTCTCTCCTTCCTTTCTGGAAGGCTCAGTGGGCCCCACCCCTCCCTCCAGCCACCTG
Downstream sequence
GACCTGCCCAGCGCTCTTGTGCAACAGGTAAAGCCTACCTGTAGCAACAACAGATCTGGGAAGGCTGCAGAGGGCACGATGGGGTCTGGATCGAGGGCGG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate