Basic Information
VIS ID
TVIS30014395
Fusion event
HIV-PLEC integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145034173/143960005 (Hg38)
End
145034173/143960005 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
PLEC
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-6796-5p ; hsa-mir-7109-5p ; hsa-mir-3978 ; hsa-mir-6790-5p ; hsa-mir-6742-5p ; hsa-mir-4658 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-3151-5p ; hsa-mir-491-5p ; hsa-mir-4792 ; hsa-mir-6842-5p ; hsa-mir-7110-5p ; hsa-mir-6752-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-3659 ; hsa-mir-4487 ; hsa-mir-574-5p ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-875-3p ; hsa-mir-6835-3p ; hsa-mir-1266-5p ; hsa-mir-127-5p ; hsa-mir-1293 ; hsa-mir-1827 ; hsa-mir-1909-3p ; hsa-mir-3174 ; hsa-mir-323a-5p ; hsa-mir-3612 ; hsa-mir-363-5p ; hsa-mir-3664-3p ; hsa-mir-4257 ; hsa-mir-4433a-3p ; hsa-mir-4433b-3p ; hsa-mir-4443 ; hsa-mir-4459 ; hsa-mir-4483 ; hsa-mir-4518 ; hsa-mir-4651 ; hsa-mir-4768-3p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-608 ; hsa-mir-650 ; hsa-mir-6722-3p ; hsa-mir-6745 ; hsa-mir-6782-5p ; hsa-mir-6804-5p ; hsa-mir-6808-5p ; hsa-mir-6847-5p ; hsa-mir-6854-5p ; hsa-mir-6880-5p ; hsa-mir-6893-5p ; hsa-mir-7847-3p ; hsa-mir-940
Nearest miRNA
hsa-mir-1204/Upstream/14726; hsa-mir-10400/Downstream/97316;
Nearest TSS
ENST00000518652/Upstream/1206; ENST00000530898/Downstream/13524;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/5821, chr8-CpG: 401/Downstream/13120
Upstream sequence
gaagtggaggttgcattgagctgagatcatgccactacactccagcttgggcgacagagtgagactccgtctcaaaaaaaataaaaaagaaCTggccagg
Downstream sequence
cacgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcaggcagatcacctgaagttgggagttcgagaccagcctgaccaacatggaga
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate