Basic Information
VIS ID
TVIS30014399
Fusion event
HIV-RBM39 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
34297713/35709791 (Hg38)
End
34297713/35709791 (Hg38)
Orient
-
Location type
Intronic
Target gene
RBM39
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-484 ; hsa-mir-221-3p ; hsa-mir-26a-5p ; hsa-mir-22-3p ; hsa-mir-369-5p ; hsa-mir-382-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/255694; hsa-mir-1-1/Downstream/2806772;
Nearest TSS
ENST00000382410/Upstream/1803; ENST00000617560/Downstream/775;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/10012, chr20-CpG: 81/Downstream/31777
Upstream sequence
TAAAATTGTAAATACTGCACATCAAAAAGCTGTAACAGTTTCCATGATTTCCCAATTTAGGAAGAACATCACCATTGGGAAATACACCATTCCAACAGTA
Downstream sequence
TGCATATATTATTTTTTTAAGGACTTTTCAAAGATTTAACTTGTCAAATCTAGCCCATAATGGGGCAACTTGATTATTGATTTCCTGGCCTAGTGTAAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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