Basic Information
VIS ID
TVIS30014402
Fusion event
HIV-TMEM116 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
112441862/112004058 (Hg38)
End
112441862/112004058 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
TMEM116
miRNAs that regulate target gene
hsa-mir-127-5p
Nearest miRNA
hsa-let-7i/Upstream/204153; hsa-mir-1178/Downstream/33541;
Nearest TSS
ENST00000382841/Upstream/114825; ENST00000553161/Downstream/1927;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/161148, chr12-CpG: 94/Downstream/9043
Upstream sequence
CATAATTGATATAAAATAAACTGCATTAAAAAAAtttttagacacagggtcttgctatgtcagccaggctggagtgcagtggtgtcattatagctcaacg
Downstream sequence
taaccttgaactcctgggccctggtgatcctcctgtctcagcctcctgagtagctaggactataggtgtgaatcaccacaactggctaattattttattt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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