Basic Information
VIS ID
TVIS30014407
Fusion event
HIV-METTL9 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
21626834/21615513 (Hg38)
End
21626834/21615513 (Hg38)
Orient
+
Location type
Intronic
Target gene
METTL9
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1225/Upstream/109378; hsa-mir-11401/Downstream/2587603;
Nearest TSS
ENST00000527434/Upstream/2813; ENST00000569290/Downstream/2385;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/15140, chr16-CpG: 37/Downstream/48442
Upstream sequence
gagacggggtttcaccatgttgcccagctggtctcaaacacctggtttcaagagatcctcccacctcggcctcccaaaatgctgggattacagacgtgag
Downstream sequence
ccaccatgcccagccTCTAGTGCCTATAAATGTAGACCAGTCAGATGAACTTGTGAGCTCTGAGCTCAGGTGACCTCTTGTTCTAGAATTTTATAATTAT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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