Basic Information
VIS ID
TVIS30014409
Fusion event
HIV-ARHGEF6 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
135828838/136746679 (Hg38)
End
135828838/136746679 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGEF6
miRNAs that regulate target gene
hsa-mir-30c-5p ; hsa-mir-877-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-1253 ; hsa-mir-6760-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-5197-3p ; hsa-mir-888-5p ; hsa-mir-371a-5p
Nearest miRNA
hsa-let-7f-2/Upstream/195719; hsa-mir-105-1/Downstream/1921032;
Nearest TSS
ENST00000429181/Upstream/98452; ENST00000478471/Downstream/20664;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/248739, chrX-CpG: 104/Downstream/20192
Upstream sequence
gcagggaccatagctttgacattttttgtagcacctggcgatgctgggcacacaGCCTCTTGACTCTACAACAGTTTGAGcagcaagcctcgtgcttggg
Downstream sequence
cataagggctctgtagtcattcagatgtgggtctgaatcccaactcagcgactaactttctagttgggcaactgttggcctgactttccttatctgtaat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate