Basic Information
VIS ID
TVIS30014410
Fusion event
HIV-BTBD7 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
93727286/93260940 (Hg38)
End
93727286/93260940 (Hg38)
Orient
-
Location type
Intronic
Target gene
BTBD7
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-218-5p ; hsa-mir-21-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-3658 ; hsa-mir-374a-5p ; hsa-mir-142-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-887-3p ; hsa-mir-3653-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-1248 ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1260a/Upstream/15994650; hsa-mir-1185-1/Downstream/687286;
Nearest TSS
ENST00000550708/Upstream/42259; ENST00000342144/Downstream/32988;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/37021, chr14-CpG: 117/Downstream/71423
Upstream sequence
ctgcacccagccTACTTTCTACAACATTTAAAAATAAACAATGAATGCttttttatttgtactctttttttttttgagtcttgctctttcacccatgtgg
Downstream sequence
agtgcaatagtgcaatctcagctcactgcaacctctgcctcccaggttcaagtgattctcatgcctcagtctcccgagtagctgggagtacaggcgcgtg
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate