Basic Information
VIS ID
TVIS30014414
Fusion event
HIV-DUSP16 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12643957/12491023 (Hg38)
End
12643957/12491023 (Hg38)
Orient
-
Location type
Intronic
Target gene
DUSP16
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-192-5p ; hsa-mir-6818-5p ; hsa-mir-580-3p ; hsa-mir-4693-5p ; hsa-mir-4738-3p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-606
Nearest miRNA
hsa-mir-1244-3/Upstream/378987; hsa-let-7i/Downstream/273626;
Nearest TSS
ENST00000382841/Upstream/5670; ENST00000540224/Downstream/15164;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/133529, chr12-CpG: 111/Downstream/70676
Upstream sequence
tacataattataataacaagtccagtggcctaaagttcgagaacaaacacaactgattcttggtaagtatactattcaaatggtggaggcagacgtgcta
Downstream sequence
cagcaaagagcccactcatgcagcaggcattcaCCTTCCAAAGATGTGGGGAAAAGATGTCGTGAAATCTCTGGAGTCAGTTAAGAAAGTTTCTAAAGTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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