Basic Information
VIS ID
TVIS30014415
Fusion event
HIV-ADK integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
76224938/74465180 (Hg38)
End
76224938/74465180 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADK
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-5571-5p ; hsa-mir-4674 ; hsa-mir-6878-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-6749-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-4437 ; hsa-mir-4757-5p ; hsa-mir-6744-3p ; hsa-mir-378g ; hsa-mir-4680-5p ; hsa-mir-532-3p ; hsa-mir-212-5p ; hsa-mir-6513-3p ; hsa-mir-1224-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-6813-3p ; hsa-mir-498 ; hsa-mir-592 ; hsa-mir-4279 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-597-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1914-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1265/Upstream/1744080; hsa-mir-107/Downstream/1087278;
Nearest TSS
ENST00000439456/Upstream/288494; ENST00000467840/Downstream/60184;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/287950, chr10-CpG: 35/Downstream/348257
Upstream sequence
gagaaaaataaaacagaaaagagtgttcaggtctagcatgaaaggttacactttcaaatctgatcattagggaaagtctcacccaagacagtgatgttta
Downstream sequence
aaaatatttcaagaagcaagttgtgcacatattagggagaaaaacaatcagtgaataaatagcaagtataaagtctctatgccaggagcatagcatgttt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate