Basic Information
VIS ID
TVIS30014422
Fusion event
HIV-TRAF2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139785955/136891503 (Hg38)
End
139785955/136891503 (Hg38)
Orient
-
Location type
Intronic
Target gene
TRAF2
miRNAs that regulate target gene
hsa-mir-502-5p ; hsa-mir-371a-5p ; hsa-mir-4519 ; hsa-mir-3120-3p ; hsa-mir-4279 ; hsa-mir-6851-3p ; hsa-mir-6081 ; hsa-mir-6886-3p ; hsa-mir-4722-5p ; hsa-mir-5008-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-5088-3p ; hsa-mir-4530 ; hsa-mir-4459 ; hsa-mir-4695-5p ; hsa-mir-6165 ; hsa-mir-892b ; hsa-mir-34a-5p
Nearest miRNA
hsa-let-7a-1/Upstream/4700; hsa-mir-3621/Downstream/277683;
Nearest TSS
ENST00000422679/Upstream/1968; ENST00000474950/Downstream/8977;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1262, chr9-CpG: 31/Downstream/16462
Upstream sequence
agccatttttttgtgtttttggtagagacagggtttcatcatgttccccaggctggtcttgaactcctgagctcaagcaatctgcctacctcggcctccc
Downstream sequence
aaagtgctgggattataggtgtgagccaccatgcctggccCATTTTTGTGGTTCTTTTATGTCTGACAGGCATGCCTAGGGCAGGGAGGGCACACCTCTG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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