Basic Information
VIS ID
TVIS30014423
Fusion event
HIV-DOCK2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
169102339/169675335 (Hg38)
End
169102339/169675335 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
DOCK2
Nearest miRNA
hsa-mir-10397/Upstream/411641; hsa-mir-10523/Downstream/353153;
Nearest TSS
ENST00000502646/Upstream/38044; ENST00000519734/Downstream/19844;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/37637, chr5-CpG: 31/Downstream/430741
Upstream sequence
CAGGGCCTCCTGGAGTGGAGTCCAGGGCCTCACCACTCTGCTACTTGGATAGCATTTGAGAACTATAAGGACCTTCCCTCCCTCCTGATCTTTTGAATGG
Downstream sequence
CTTCCAAACATTCTGTTCATTTGTTCattcattcctaccacaaacatgtattgaggacttatagttggctggatttcctgctaggtattggggctgtaga
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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