Basic Information
VIS ID
TVIS30014426
Fusion event
HIV-ADCY1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
45737219/45697620 (Hg38)
End
45737219/45697620 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADCY1
miRNAs that regulate target gene
hsa-mir-423-3p ; hsa-mir-331-3p ; hsa-mir-320a ; hsa-let-7b-5p ; hsa-mir-212-3p
Nearest miRNA
hsa-mir-1183/Upstream/815820; hsa-mir-10399/Downstream/11258165;
Nearest TSS
ENST00000635602/Upstream/13235; ENST00000457280/Downstream/175462;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/121715, chr7-CpG: 33/Downstream/29294
Upstream sequence
gctggggttacaggcatgcgccaccacgcccggctaattttgtatttttagtagagatggggtttctccatgttggtcaggctggtcttgaattcctgac
Downstream sequence
cttagatgatctgcccgcctcagcttcctaaagtgctgggattacaggcgtaagccactgcgcccagccCTCTTTACCTTTTAAAATGGCATCCCCATCT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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