Basic Information
VIS ID
TVIS30014428
Fusion event
HIV-SOX5 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
24490220/24337286 (Hg38)
End
24490220/24337286 (Hg38)
Orient
-
Location type
Intronic
Target gene
SOX5
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-194-5p ; hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-96-5p ; hsa-mir-130a-3p ; hsa-mir-181a-5p ; hsa-mir-132-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-1231 ; hsa-mir-632 ; hsa-mir-4288 ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4766-5p ; hsa-mir-1277-5p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-574-5p ; hsa-mir-5580-3p ; hsa-mir-555 ; hsa-mir-374a-3p ; hsa-mir-136-3p ; hsa-mir-4704-5p ; hsa-mir-3529-3p ; hsa-mir-6759-5p ; hsa-mir-6793-5p ; hsa-mir-6748-5p ; hsa-mir-933 ; hsa-mir-4783-5p ; hsa-mir-3607-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/124791; hsa-let-7i/Downstream/1536734;
Nearest TSS
ENST00000382841/Upstream/113999; ENST00000536131/Downstream/20144;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1712007, chr12-CpG: 92/Downstream/224736
Upstream sequence
TTTTTTGTACACATGGCTTTCAACATCTGAGTAAATGAACAATATTCATCTTACTTTCTATAAATCAGACACTATTTCTAGTTCACAATCCCCAGATGTA
Downstream sequence
TCATTAACATCATAATCTAGTTTATTGGCATTACACCTCTAAATCTGAtttttcttttttttttttttaagagagagagagtttcactctgttgcccagg
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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