Basic Information
VIS ID
TVIS30014432
Fusion event
HIV-ARHGAP35 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47463828/46960571 (Hg38)
End
47463828/46960571 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ARHGAP35
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-mir-181b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-574-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-147a ; hsa-mir-3611 ; hsa-mir-6818-5p ; hsa-mir-6867-5p ; hsa-mir-4670-3p ; hsa-mir-6749-3p ; hsa-mir-6763-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-5587-3p ; hsa-mir-4707-5p ; hsa-mir-5196-3p ; hsa-mir-6501-3p ; hsa-mir-6768-3p ; hsa-mir-1827 ; hsa-mir-3612 ; hsa-mir-4443 ; hsa-mir-4524a-3p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-5091 ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548t-3p ; hsa-mir-650 ; hsa-mir-6786-3p ; hsa-mir-6808-5p ; hsa-mir-6880-5p ; hsa-mir-6893-5p ; hsa-mir-7847-3p ; hsa-mir-940 ; hsa-mir-198 ; hsa-mir-210-3p ; hsa-mir-6774-3p ; hsa-mir-4330
Nearest miRNA
hsa-mir-10395/Upstream/251217; hsa-let-7e/Downstream/266371;
Nearest TSS
ENST00000633603/Upstream/23251; ENST00000596593/Downstream/29013;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/99026, chr19-CpG: 40/Downstream/43478
Upstream sequence
CATTCTTTGGTCTACATGCAGAGAAGAGAGTTTCTTATTAGAGAACAGATTGGAGAAAAAAATAGGGCTTTTACTGTTTATTCCACGTATTTCTGTATTG
Downstream sequence
TGTGAAAAGTAATTTAGCAATGAACACGTATTTTGTTAAAAAAAATTGTAGAATCGTTAGAAGTAAAAAGTAAAGTCATTTTCTCATTctcaaagttacc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate