Basic Information
VIS ID
TVIS30014440
Fusion event
HIV-ZBTB17 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
16292676/15966181 (Hg38)
End
16292676/15966181 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ZBTB17
miRNAs that regulate target gene
hsa-mir-544a
Nearest miRNA
hsa-mir-12136/Upstream/3387158; hsa-mir-101-1/Downstream/892768;
Nearest TSS
ENST00000473358/Upstream/13208; ENST00000329454/Downstream/9898;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/21094, chr1-CpG: 85/Downstream/9226
Upstream sequence
AAGTTCTTTCTTACTTTAAATCATTTGCCAAGCATTAATTTGGGCTGCTGACTGAGTCACAGTAACGGGGGAAAATCCCTGAGGGGCCCACATGGCCCCG
Downstream sequence
AGACTACAGAAATGAGAAGTGCTTTGCTCTCTGAGCTCTGGTGATACAGCTTCCCATGGGGCAGGCTGGCGAAATTCGAGTGGAGCCTGCCACTCGGGAC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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