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TVIS30014456
Basic Information
VIS ID
TVIS30014456
Fusion event
HIV-PIK3CD integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
GRCh37/hg19
Start
9755257/9695199 (Hg38)
End
9755349/9695199 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
PIK3CD
miRNAs that regulate target gene
hsa-mir-7-5p
;
hsa-mir-30a-5p
;
hsa-mir-10b-5p
;
hsa-mir-125b-5p
;
hsa-mir-663a
;
hsa-mir-199a-5p
;
hsa-mir-101-3p
;
hsa-mir-25-3p
;
hsa-mir-25-5p
;
hsa-mir-32-5p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-4459
;
hsa-mir-500a-3p
;
hsa-mir-582-5p
;
hsa-mir-6087
;
hsa-mir-655-5p
;
hsa-mir-658
;
hsa-mir-6807-5p
;
hsa-mir-92a-3p
;
hsa-mir-92b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-3622b-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4690-3p
;
hsa-mir-4768-3p
;
hsa-mir-4786-5p
;
hsa-mir-544b
;
hsa-mir-5685
;
hsa-mir-6765-3p
;
hsa-mir-7162-3p
Nearest miRNA
hsa-mir-12136/Upstream/543422; hsa-mir-101-1/Downstream/272182;
Nearest TSS
ENST00000473358/Upstream/7023;
ENST00000481137/Downstream/14999;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/5029
,
chr1-CpG: 26/Downstream/20451
Upstream sequence
aataagctgttaggtattaagatagcagaagtaaaaatagaagaagtaaaaatttcaacagaagagttggaagagtgaaaaacaaatttccagaaagtag
Downstream sequence
caagaaaaaaaggcaagagaaacggaggaaggaaaagtatgtaggaaacaattctagaactgaaggcatttctacttttaaacagtctcgaagtagtacc
Target sequence
aacacaaagacttaagagatggaaaataggaaagaaaatatagaaaaatttgacttcagtccaggagacccagcatgcaccacataggagct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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