Basic Information
VIS ID
TVIS30014457
Fusion event
HIV-UBE4B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
End
10140682/10080429 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/112971; hsa-mir-101-1/Downstream/1948729;
Nearest cancer related gene
UBE4B(TSG, No orient, 0)
Upstream sequence
gaatcgcttgaacccaggaggcagaggttgcagtgagccaagatcccaccactgcactccagtgtggtgagagtgagaatccatctcaaaaaaaaaaaaa
Downstream sequence
ttattccaaatagccaagatatggaagcaacctaaataatccatcttcagatgaatgggaaaagaaactgtggtatgtatccacaatggaatattattca
Target sequence
gaaagaaagaaagaaaGAAAATTCTAtgttggtgagagtgtaaatttatatagccattttacaaaacaatatggaggtccctcagaaaactaaaaacagagctaccatatgatctggcagtcccactgagtatatatccaaagaaattaagattcatatgctgaagagatacctctactcatgttcattgcagca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate