Basic Information
VIS ID
TVIS30014458
Fusion event
HIV-KIF1B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.22
Reference genome
End
10415420/10355658 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/388200; hsa-mir-101-1/Downstream/1673500;
Nearest cancer related gene
KIF1B(TSG, No orient, 0)
Upstream sequence
CTTAAATGATTTTTAGAGTTTCAAATTATTTTTTCATTCCATTTGCTAAACTTGTCAGTTTTATTCTTAGACTCTTTCAAGTTTTCCTCTTCTACATTAC
Downstream sequence
AAAGTAGAATGTTTCTCCCTTCATTTCATACAGAATCTCAGGTTTTGTTTTCTGTTTTCCTCTTTATCTGTCTTCTCTCCGTCAAAAGCATGAAGGGTTT
Target sequence
TTTGCAGGCTCTTTCTTGATAAGGATATTCCTAGGTATTGTCTGTTTGCTTTTTTGCACGTAGGATTCTAGTTTATCAGAATGCTTTCTGTCTTATGTTGCTTTGCCATTTTAATTTTGTAGTCCCCTCCCCATGTAAACCTACTGTACCTAGGATAGAGTAGACCCTGTTCTGTACCCTAAGAAGCGTATAGCTTCTTAAATGATTTTTAGAGTTTCAAATTATTTTTTCATTCCATTTGCTAAACTTGTCAGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate